Clinical Veterinarian

eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.

The Clinical Veterinarian maintains clinical oversight of the research grade pig population and surrogate herd for the eGenesis site. This role places a strong emphasis on herd health management, disease prevention and clinical decision making to ensure the stability and wellbeing of the pig population. Additionally, this individual will manage personnel of the veterinary team, support in vivo studies and advise on regulatory compliance related to animal activities.

Clinical Veterinary Care and Herd Health

Lead herd health management, including disease prevention, diagnosis, and treatment across donor and surrogate pig populations

Provide clinical support for surrogate herd including routine medical cases, ultrasound diagnostics according to study designs or for clinical assessments

Support epidemiological tracking and disease monitoring to proactively manage population health

Evaluate neonate piglets daily and work with neonatal care team to implement treatment plans for any health concerns that arise

Perform necropsies and submit diagnostic samples for relevant research and clinical cases to ensure health of donor and surrogate herds or provide findings to development team

Collaborate with internal teams and external partners and vendors to support animal health and sourcing

Participate in all surgery activities and advanced reproductive procedures

Perform other duties and assume additional responsibilities as assigned

Animal Care Program Leadership

Develop a veterinary science department with expansion according to research needs in support of eGenesis xenotransplantation platform

Collaborate with veterinarians and leadership across other eGenesis sites to manage veterinary care and population health programs

Facilitate staff development in area of laboratory animal science

Oversight of Wisconsin barns to meet IACUC standards and USDA regulations

Participate in IACUC activities including inspections, advising of team members, interpretation of regulatory requirements, and serving as alternate veterinarian on committee

Draft, review, and revise SOPs relevant to the neonatal, veterinary, and general animal care activities

Participate in scientific and management meetings with Cambridge and Indiana sites, including donor animal allocation, preclinical development, and regulatory

Serve ad hoc on internal eGenesis Publication Committee for review, collaboration, or preparation of manuscripts

Develop and provide an annual training program to the Animal care, Neonatal and Vet tech team to assure compliance with animal welfare regulations and animal treatment plans

Provide personnel management including goal setting, performance reviews, conflict resolution, scheduling and training documentation oversight

Compliance, Biosecurity and Safety

Ensure compliance with company biosecurity practices to safeguard health of all animals produced by eGenesis

Work in collaboration with veterinarians to identify potential biosecurity and husbandry process improvements in the neonatal area

Promote and adhere to safety in the workplace and report unsafe acts, ensure equipment is maintained correctly, report all accidents/incidents, inspect work area and take remedial action to minimize or eliminate all hazards.

Promote and adhere to the eGenesis animal welfare policies

Follow all applicable regulatory requirements (USDA, FDA, OLAW) regarding animal welfare and ensure humane care according to the Guide for the care and use of Laboratory Animals and the Animal Welfare Act