Posted 2 months ago
Molecular Biologist / Research Scientist
AI Summary
A molecular biologist / research scientist designs and runs end-to-end wet lab workflows for an automated biology platform, including selection design, library construction, FACS screening, and interpreting population-level results.
About this role
The role
We are building an automated biology platform and, and we are looking for a molecular biologist / research scientist to handle the core wet lab work: selection design, library construction, and readouts.
Responsibilities
Run end to end workflows, library through selection to characterized hits
Design selection strategy: stringency schedules, bottlenecks, counter-selections
Design FACS sorting and screening strategies, and interpret population trajectories across rounds
Must-haves
Cell culture: hands-on experience, ideally with yeast.
Molecular cloning: fundamentals (PCR amplification, Gibson assembly, Golden Gate assembly, transformations); experience with sequencing services.
Flow cytometry/FACS: gating strategies, staining, sample loading.
Nice-to-haves
Yeast genetics and surface display · OrthoRep or other continuous hypermutation systems · phage display or PACE · SPR/BLI · NGS library prep and analysis · protein expression and purification · Opentrons, Hamilton, Tecan, or eVOLVER-class hardware.
If you have never worked in yeast, apply anyway. We would rather hire for selection judgment and long-run discipline, and teach the organism.
Skills
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