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Posted 3 months ago

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Open Application for Scientists and Research Associates

San FranciscoOn-siteFull-time

AI Summary

A Scientist/Research Associate at Rezo Therapeutics executes integrated biology and data-driven projects across proteomics, genetics, chemical biology, and computational analysis to support drug discovery and build platform capabilities.

About this role

About Rezo Therapeutics
Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it.
We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.
Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements. If you’re passionate about team science and breaking down barriers to progress in drug development, please consider joining us!

If you do not see a job listing that matches your specific background, please apply to this posting as we will be looking for exceptional individuals in the following areas:

Proteomics

  • Develop industry scale assays using in-house mass spectrometers
  • Execute platform projects centered on PPI mapping, proximity labeling, post-translational modification and abundance proteomics
  • Support drug discovery campaigns and develop target-based screens
  • Genetics

  • Develop multimodal single and combinatorial genetic screens using CRISPR technologies
  • Collaborate with target discovery teams to provide genetic support for targets and drug MOA
  • Chemical Biology and Protein Sciences

  • Develop HTS small molecule screening campaigns and create robust target assays for drug development
  • Drive enzymology, biophysics and protein binding analysis efforts
  • Help build out the structural biology platform (including crystallography & Cryo-EM)
  • Develop chemical biology tools to map ligandable pockets and aid in drug development
  • Cancer Biology

  • Implement cutting edge molecular and cellular techniques to determine target functions in cell-based solid tumor models
  • Develop data packages to prioritize targets and nominate candidates to the drug discovery stage
  • Individuals with expertise in oncogene/tumor suppressor pathways and/or drug resistance are especially encouraged to apply
  • Computational Biology, Data Science

  • Develop novel algorithms and apply deep learning-based approaches to network and proteomics datasets
  • Implement cloud infrastructure, pipelines, and UI/UX for data analytics
  • Conduct bioinformatic and statistical analyses of large, multimodal datasets
  • Skills

    BioinformaticsBiophysicsCloud InfrastructureCRISPRCryo-EMCrystallographyDeep LearningEnzymologyHTS ScreeningMass SpectrometryNetwork BiologyProtein Assays

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