Posted 11 months ago
Postdoctoral Research Associate - Immunology
AI Summary
Conducts research on innate immune system signaling during infections, inflammatory diseases, and cancers, focusing on pathways such as NLRs, inflammasomes, and PANoptosis and their connections to adaptive immunity.
About this role
A postdoctoral position is available at St. Jude Children’s Research Hospital for an outstanding and highly motivated candidate to investigate the cellular signaling in the innate immune system during infections, inflammatory diseases, and cancers.
Summary
St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.
We are particularly interested in dissecting the signaling pathways involved in innate immune responses and cell death (NLRs, caspases, inflammasomes, and inflammatory cell death, PANoptosis) and understanding how these pathways connect to adaptive immunity (T cells). Please see the following articles:
Cell (2023) 186(13):2783-801.e20.
Science Immunology (2022) 7(74):eabo6294.
Nature (2021) 597(7876):415-9.Cell (2021) 184(1)_149-168.e17.
Cell (2020) 181(3):674-687.e13.
Nature (2019) 573(7775):590-4.
Nature Microbiology (2019) 4(2):316-27.
Cell (2018) 173:1–14.
Journal of Experimental Medicine (2018) 215(4):1023-34.
Nature (2016) 540:583-7.
Science Immunology (2016) 1(2):aag204-5.
The ideal candidate will have experience with immunology or cell/molecular biology methodologies, such as:
Macrophage and primary cell culture
T cell analyses
Western blotting
qPCR
CRISPR
Co-immunoprecipitation experiments
The laboratory of Dr. Thirumala-Devi Kanneganti offers a remarkable training environment for postdoctoral fellows focused on the innate immune system and its connections with adaptive immunity, including an opportunity to collaborate with researchers in the departments of Immunology, Host Microbe Interactions, and cancer biology. Generous salary support and a benefits package that includes professional development funds for journal subscriptions and travel to meetings are available. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, metabolomics, RNAseq, transgenic/knock-out technology, and animal facilities from biosafety level 2 to enhanced biosafety level 3.
Minimum Education
Candidates should have a recent PhD, DVM, MD/PhD in biomedical sciences with practical experience in immunology (innate and adaptive immune responses) and must be hard working and highly motivated.
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Skills
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