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Posted 26 days ago

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Research Associate (Organ Perfusion)

Bay AreaOn-siteFull-time

AI Summary

Research Associate focused on developing organ perfusion protocols, perfusion/isolation, and viability evaluation for whole organ preservation. Collaborates across biology, physics, and chemistry to advance cryopreservation research.

About this role

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About The Role
We are seeking an experienced and dedicated full-time Research Associate to join our whole organ preservation team. As Research Associate, you will play a vital role in the scientific progress of our research program. The primary focus of this role is on developing organ perfusion protocols, with an emphasis on organ isolation, preservation, and viability evaluation. The person in this role is encouraged to take on significant ownership of specific technical challenges.
You will have the opportunity to collaborate with scientists and engineers across the company on variety of methods inspired by first principles of biology, physics, and chemistry. Creative scientific engagement is encouraged, and new avenues for discovery and optimization are continuously supported.

Responsibilities

  • Perform pig organ isolation and ex-vivo evaluation protocols, including perfusion and histology
  • Work within scientific team to evaluate health of organs following cryopreservation
  • Survey literature and conduct experimental tests to answer critical questions towards optimizing preservation protocol
  • Ensure accurate sample processing and on-time data reporting

    • Qualifications

  • You have an undergraduate degree in a STEM field, or significant STEM-related training
  • You have 2 years experience and an excellent record of success performing complex and demanding laboratory procedures, ideally with training in ex vivo organ perfusion and viability assessment.
  • You have demonstrated a passion for rapid problem solving and exploration of novel topics / protocols.
  • Desire to work in a laboratory setting.
  • You have experience or interest in physiology, with a creative approach to understanding and manipulating functions of organs.
  • You demonstrate agency, problem solving, passion for discovery, and a drive to push the boundaries of science through meaningful involvement in an ambitious project.

    • Benefits

  • Opportunity for outsized impact creating the future as an early team member
  • Generous medical, dental and vision insurance coverage
  • Flexible time off and paid holidays
  • Competitive compensation package, including salary and equity
  • 401(k) retirement savings plan
  • FSA and commuter benefits
  • Subsidized lunch daily

    • Skills

    BiologyCryopreservation ConceptsData ReportingExperimental DesignEx Vivo Organ PerfusionFirst PrinciplesHistologyLiterature SurveyOrgans IsolationPerfusion ProtocolsPhysiologySample ProcessingViability Assessment

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