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Posted 4 months ago

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Research Scientist, Rodent Neural Imaging

San FranciscoRemoteFull-time

AI Summary

A research scientist designs and executes rodent experiments to characterize ultrasound neuromodulation effects on brain circuits and behavior, collecting and analyzing neural and behavioral data to link neural activity changes to clinical-relevant outcomes.

About this role

About Nudge

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're starting with an approach that we believe can help the most people the fastest, and also allow us to learn as much about the brain as possible: developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth. This is a vertically integrated effort building cutting-edge hardware, software, and research capabilities to create products that can benefit millions — and eventually billions — of people.

To succeed, we need to assemble world-class teams across everything we do. We hire people who are exceptional at their craft, believe hard things are worth doing, and execute relentlessly — people who expect the highest levels of both rigor and integrity from each other.

About the role

As a research scientist focused on rodent behavior and neural imaging at Nudge, you will:

  • Design and execute experiments in rodents to characterize the effects of ultrasound neuromodulation on brain circuits and behavior

  • Collect and analyze behavioral and neural data, with techniques such as electrophysiology, calcium imaging and/or fiber photometry

  • Develop and validate experimental paradigms linking neural activity changes to behavioral and physiological responses with clinical relevance

  • Optimize ultrasound stimulation parameters for specific brain circuits and cell types to achieve targeted neuromodulation

  • Translate preclinical findings to inform human neuromodulation studies

About you

  • PhD or postdoc in neuroscience, biomedical engineering or similar engineering discipline

  • Exceptional proficiency in ultrasound neuromodulation, functional ultrasound neuroimaging, optogenetics, electrophysiology, two-photon microscopy, or fiber phototometry in animal models

  • Experience with automated behavioral tracking and analysis or computational analysis of neural + behavioral data

  • Experience designing experiments informed by ultrasound physics and acoustic field modeling is preferred

  • Demonstrated history of exceptional technical contribution

  • High integrity and strong professional judgement

Skills

Acoustic Field ModelingAutomated Behavioral TrackingCalcium ImagingElectrophysiologyFiber PhotometryFunctional Ultrasound NeuroimagingOptogeneticsUltrasound Neuromodulation

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