Jobless Developer

Scientist Cell Biology

GhentOn-site

AI Summary

Designs and executes cell-based assays to screen and characterize novel antibody conjugates for autoimmune disease and cancer, troubleshooting experiments and collaborating with cross-functional discovery teams.

About this role

As a Scientist in the Cell Team, you will play a key role in design, troubleshooting and execution of cell-based assays for the screening, characterization and preclinical evaluation of novel antibody conjugates for the treatment of autoimmune disease and cancer. Your ability to work independently, manage multiple experiments in parallel, and contribute to innovative scientific strategies will be essential to our success.

Key Responsibilities

  • Design and execute molecular and cell biology experiments to screen and characterize novel therapeutic candidates.
  • Develop and execute cell-based assays to assess biological activity and mechanism of action of advanced therapeutic candidates.
  • Work closely with the discovery team to support the characterization of new molecules.
  • Troubleshoot technical challenges of the biology team and develop solutions to improve workflows and experimental outcomes.
  • Maintain accurate and detailed laboratory records, documenting protocols, results and observations.
  • Collaborate with cross-functional teams, including computational biology, structural biology, and protein engineering, to drive screening and preclinical programs forward.
  • Contribute to technical documents such as study plans, study reports, protocols, and SOPs within the Quality Management System.
  • You will use a variety of technologies: cell culture (cell lines and primary cells), reporter assays, flow cytometry, ELISA, Luminex, High content imaging.
  • You will be an essential part of a close-knit, fast-paced company with the ambition of bringing a new class of therapies to patients worldwide.

Skills, Knowledge & Expertise

  • PhD in Biology, Immunology, Biotechnology, or a related field with a minimum of 2 years of relevant experience in industry.
  • Demonstrated practical experience in screening and cell-based assay development.
  • Experience with primary cells (PBMCs, B cells and T cells).
  • Expertise in multiplex flow cytometry and/or cell imaging methods.
  • Experience in high throughput screening is a plus.
  • Self-motivated and enthusiastic personality with positive attitude, curiosity-driven mindset, and a passion for working in the laboratory and experience of first-hand scientific discovery.
  • Strong analytical and problem-solving skills with the ability to troubleshoot and optimize experiments, also of others.
  • Strong communication skills and ability to work within a result-driven team with diverse technical backgrounds.
  • Ability to work both independently and as part of a collaborative, fast-paced team.
  • Enthusiasm to be part of a larger organization with a strong focus on rapidly moving projects forward and bringing new therapies to patients.
  • Proficiency in Microsoft Office and Prism.
  • Fluency in English, both written and spoken, Dutch and/or French are a plus.

Skills

Cell CultureCell ImagingELISAFlow CytometryHigh Content ImagingHigh Throughput ScreeningLuminexMicrosoft OfficeMultiplex Flow CytometryPrimary CellsPrismReporter Assays

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