Posted 15 days ago
Scientist I
AI Summary
Scientist I at Thermo Fisher Scientific (Invitrogen) in Bangalore, India. Develops and validates recombinant antibodies through cell culture, animal immunization, titer checks, ELISA, RT-PCR, and clone selection. Manages lab operations, data integrity, and vendor relationships.
About this role
Work Schedule
Standard (Mon-Fri)Environmental Conditions
Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)Job Description
About Company:
Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity.
Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.
About Team:
Candidate will be working as part of Thermo Fisher Scientific Research and Development in the core cell culture. Core cell culture team contributes towards strengthening the company’s portfolio by supplying all the biological samples to develop and validate recombinant antibodies. We develop Knock downs and Knock outs to show the specificity of the antibody and also to very specific models for antibody validation to show specificity.
Role & Responsibilities
Purpose:
Thermo Fisher Scientific is recruiting a Scientist who can foster innovation and improve customer outcomes through development and validation of recombinant antibodies.
Responsibilities:
- Basic cell culture experience and PBMC isolation
- Understanding of immunizations in different animals and handling them
- Work with animal vendors and make sure they follow our guidelines and work as per our requirements
- Have to perform, pre-screening, titer checks, understand the concept of titer and plan immunizations accordingly.
- Identify the booster to be seeded, plan on seeding the cells
- Plan and execute ELISAs smartly
- Perform RT-PCR and analyze the data and choose the correct clone
- Initiate, plan, and execute scientific research with emphasis on Primary Screening
- Must have experience in automation in different steps of ELISA and RT-PCR
- Keep thorough inventory of antigen, Hyper immune Sera and results into data sheets and/or electronic notebooks and /or databases
- Take responsibility in whole lab management
- Responsible for data integrity, accuracy, and analysis.
- Deliver high quality results according to project schedule in support of current and/or new products
Skills and Experience
- Experimental skills with attention to detail are critical
- Cell cuture
- Immunization and animal handling experience
- Demonstrated ability to work in teams and mentor junior scientists
- Strong understanding and hands-on expertise with Titer checks and its concept and immunization schedules. The ideal candidate will have additional experience with protein conjugation skills.
- Superior communication skills, both written and oral.
- Should be a good team player, ready to learn new techniques and innovative thinker.
Candidate Requirement:
Education & Experience levels:
- Masters degree in life sciences or Master’s/ bachelaors degree in Cell Biology/Biotechnology or related Life Science with 5-6 years of research experience
- Applicants should have a strong background in animal handling techniques
Nature of experience:
- Should have a clear understanding of titers, animal behavious
- Should be able to think, work independently and execute experiments
Knowledge Required:
- GLP, GMP or any other certification in laboratory practices and EHS certification will be considered as a bonus
At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Apply today http://jobs.thermofisher.com .
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
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