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Senior Principal Scientist, Medicinal Chemistry

HyderabadOn-siteFull-time

AI Summary

A Senior Principal Scientist in Medicinal Chemistry independently drives lead optimization programs, designing novel molecules, interpreting SAR/DMPK/AI insights, and mentoring junior scientists while reporting to senior leadership.

About this role

Let’s build the future of medicine—together.

Senior Principal Scientist, Medicinal Chemistry
Hyderabad, India | Full-Time

YOUR ROLE

As a Senior Principal Scientist, Medicinal Chemistry at Enveda, you will independently drive lead optimisation programmes — designing novel molecules, interpreting SAR, and shaping drug discovery strategy across multiple programmes. You will work at the intersection of synthetic chemistry, DMPK, biology, and AI-enabled design while mentoring the next generation of medicinal chemists. Reporting to the Director/AVP of Chemistry, your scientific ownership will directly advance our mission to deliver hope to patients everywhere.

WHAT YOU'LL DO
  • Independently design novel molecules, interpret SAR/SPR, and generate design hypotheses to drive lead optimisation programmes

  • Integrate biology, DMPK, and AI insights into compound design; use AI-enabled molecular design tools to accelerate discovery

  • Lead multiple discovery programmes with full scientific ownership and present strategy to cross-functional global teams

  • Mentor junior scientists in medicinal chemistry thinking, scientific communication, and decision-making

  • Ensure compliance with Enveda notebook SOPs, internal IP standards, and database requirements

WHAT WE'RE LOOKING FOR

  • PhD in Organic or Medicinal Chemistry from a leading research institution with 12-15 years of medicinal chemistry experience in CRO or integrated drug discovery

  • Demonstrated track record of independently driving lead optimisation and delivering preclinical candidates

  • Expert practical skills in synthetic organic chemistry, route design, and SAR/DMPK-informed decision-making

  • Strong rational drug design experience including novelty evaluation and IP awareness

  • Outstanding scientific presentation and communication skills; comfortable representing programmes to global teams

  • We hire for trajectory, not just credentials. If you meet most of the above and care deeply about this problem, we want to hear from you.

    ABOUT ENVEDA

    We're a clinical-stage, AI-enabled biotech discovering medicines four times faster than the industry standard.
    We recently raised $150M in a Series D, reached unicorn status, and advanced our first drug into Phase 2 trials. Forbes named us one of America's Best Startup Employers. Newsweek recognized us as a Top 100 Most Loved Workplace.
    We're building something rare and we're just getting started!

    Skills

    AI-enabled Molecular DesignDMPKIP StandardsMedicinal ChemistryNotebook SOPsRoute DesignSARSynthetic Organic Chemistry

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