Posted 1 month ago
Associate Director/Director, Medicinal Chemistry
San FranciscoOn-siteFull-time
AI Summary
Associate Director/Director leading medicinal chemistry programs to design small molecules for precision medicine discovery using SBDD and network biology.
About this role
About Rezo Therapeutics
Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it.
We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.
Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements. If you’re passionate about team science and breaking down barriers to progress in drug development, please consider joining us!
The Opportunity
We are seeking a highly enthusiastic and motivated Medicinal Chemistry program leader to join our Discovery team. This role will contribute to the discovery of precision medicines through the design of small molecules, cross-functional collaborations to advance projects and programs, and incorporation of new technologies to accelerate drug discovery targeting protein-protein interactions. Becoming a member of this team is an excellent opportunity to join Rezo at an early stage, help grow the Chemistry group, and expand Rezo’s discovery platform.
We are seeking a highly enthusiastic and motivated Medicinal Chemistry program leader to join our Discovery team. This role will contribute to the discovery of precision medicines through the design of small molecules, cross-functional collaborations to advance projects and programs, and incorporation of new technologies to accelerate drug discovery targeting protein-protein interactions. Becoming a member of this team is an excellent opportunity to join Rezo at an early stage, help grow the Chemistry group, and expand Rezo’s discovery platform.
Key Responsibilities:
Qualifications:
Exceptional curiosity and creativity in design of compounds, articulating hypotheses, and testing strategies.
Highly organized, with an ability to work on extremely complex problems where multiple hypotheses are being tested simultaneously in order to accelerate decision-making.
Excellent interpersonal skills, works well within a team, and communicates effectively.
As a subject matter expert, has in-depth knowledge of medicinal chemistry, synthetic organic chemistry, covalent chemistry, and a solid working knowledge of cross-functional disciplines such as ADMET optimization and building PK/PD relationships.
Thoughtful and respected mentor to junior scientists and team members.
Skills
ADMETComputational ChemistryCovalent ChemistryCross-Functional CollaborationMedicinal ChemistryPK/PDSBDDStructure-based Drug Design
