
Posted 7 months ago
Research Scientist Biochemistry with Focus Plate-Based Assays (gn)
MunichOn-siteFull-time
AI Summary
You will develop biochemical binding and functional plate-based assays and biophysical formats to support early drug discovery projects, performing experiments and reporting results to internal and customer teams.
About this role
Your mission
- You will be a member of our interdisciplinary teams alongside colleagues from project management, protein production, protein crystallography, medicinal and computational chemistry.
- Within these experienced teams you will be responsible for developing biochemical binding and functional assays as well as biophysical assay formats to support internal and customer early drug discover projects.
- Your focus is on plate-based assays for profiling and library screening, assessing target-ligand binding or ligand effect on enzymatic activity (e.g. TR-FRET, AlphaLisa, luminescence, FI, FP, FRET/BRET).
- Experience in biophysical techniques will be a plus (e.g. nanoDSF, TSA, MST, ITC, SPR).
- You will work within our state-of-the-art biochemistry and biophysics platform, performing experiments and instructing lab staff. You will analyze and report your results to our customers and internal project teams.
Your profile
- You have a PhD degree in biochemistry, biophysics or a comparable discipline.
- You are familiar with the drug discovery process from screen to lead and have 2+ years of relevant work experience in a drug discovery environment.
- You have advanced experience with biochemical and biophysical technologies including a deep understanding of enzymology and binding kinetics and with integrating them into early drug discovery programs
- You are able to plan experiments, generate and analyze biochemical/ biophysical data and report to drug discovery teams. You are experienced in discussing data from neighboring disciplines and to integrate your data in the context of drug discovery projects.
- Your positive, communicative and open personality helps you to understand other opinions, and contributes to productive project discussions with internal and customer project teams.
- Fluent English and basic German language skills are required.
Why us?
- Detail-oriented with strong organizational skills
- An innovative field of work in an exciting industry
- A long-term, responsible position in a healthy, growing, and future-oriented company
- Comprehensive onboarding to prepare you optimally for your area of responsibility
- Multicultural teams and an open corporate culture
- A competitive salary
Contact Details
Proteros biostructures GmbH
People Team
Bunsenstr. 7a, 82152 Martinsried
+49 89 700761-0
joinus@proteros.de
Skills
AlphaLISABinding KineticsBiochemistryBiophysicsEnzymologyFluorescence (FI/FRET/BRET)ITCLuminescenceMSTNanoDSFSPRTR-FRETTSA
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